Cathepsin H Protein (CTSH) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713237

This Recombinant Cathepsin H protein is expressed in HEK-293 Cells.

Quick Overview for Cathepsin H Protein (CTSH) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713237)

Target: Cathepsin H (CTSH)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Cathepsin H protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Cathepsin H (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Cathepsin H (CTSH)

Alternative Name: Cathepsin H

Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Molecular Weight: 35.1 kDa

NCBI Accession: NP_004381

Pathways: Positive Regulation of Endopeptidase Activity