CBLC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713256

Product Details

Target: CBLC (Cbl proto-oncogene C (CBLC))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CBLC protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CBLC / RNF57 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CBLC (Cbl proto-oncogene C (CBLC))

Alternative Name: Cblc,rnf57 (CBLC Products)

Synonyms: CBL-3 Protein, CBL-SL Protein, RNF57 Protein, Cbl proto-oncogene C Protein, CBLC Protein, Cblc Protein

Background: This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 52.3 kDa

NCBI Accession: NP_036248

Pathways: EGFR Signaling Pathway