CCBL1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for CCBL1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713271)
Target
See all CCBL1 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This CCBL1 protein is labelled with Myc-DYKDDDDK Tag.
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Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
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Characteristics
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- Recombinant human CCBL1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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Biological Activity Comment
- The specific activity of KATI was determined by measuring the product Kynurenic acid formation from a conversion of Kynurenine. The reaction was carried out at 37? for 15min in the buffer containing 100 mM PBS, pH7.4, 2 mM a-oxoglutarate, 40μM PLP (pyridoxal 5'-phosphate), and 0.5 mM kynurenine as the substrate.
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Cysteine-S-conjugate beta-Lyase (CCBL1) (AA 1-424) protein (His tag)
custom-made CCBL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cysteine-S-conjugate beta-Lyase (CCBL1) (AA 1-422) protein (His tag)custom-made CCBL1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cysteine-S-conjugate beta-Lyase (CCBL1) (AA 1-112) protein (GST tag)CCBL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cysteine-S-conjugate beta-Lyase (CCBL1) (AA 1-374) protein (GST tag)CCBL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cysteine-S-conjugate beta-Lyase (CCBL1) (AA 1-442) protein (His-IF2DI Tag)CCBL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cysteine-S-conjugate beta-Lyase (CCBL1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CCBL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- > 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))
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Alternative Name
- Ccbl1
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Background
- This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
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Molecular Weight
- 47.7 kDa
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NCBI Accession
- NP_004050
Target
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