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Endoglin Protein (ENG) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

This Recombinant Endoglin protein is expressed in HEK-293 Cells.
Catalog No. ABIN2713357
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for Endoglin Protein (ENG) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713357)

Target

See all Endoglin (ENG) Proteins
Endoglin (ENG)

Protein Type

Recombinant

Origin

  • 18
  • 8
  • 2
  • 1
Human

Source

  • 13
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Purification tag / Conjugate

    This Endoglin protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD105 / Endoglin (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Endoglin (ENG)

    Alternative Name

    Cd105,endoglin

    Background

    This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    65 kDa

    NCBI Accession

    NP_000109
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