L1CAM Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for L1CAM Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713465)
Target
See all L1CAM ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This L1CAM protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD171 / L1CAM (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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L1 Cell Adhesion Molecule (L1CAM) (AA 20-1120) protein (His tag)
L1CAM Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
L1 Cell Adhesion Molecule (L1CAM) (AA 20-1123) (Active) protein (His tag)L1CAM Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
L1 Cell Adhesion Molecule (L1CAM) (AA 20-1115) protein (His tag)L1CAM Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
L1 Cell Adhesion Molecule (L1CAM) (AA 1003-1114), (partial) protein (His tag)L1CAM Origin: Human Host: Yeast Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Alternative Name
- Cd171,l1cam
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Background
- The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
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Molecular Weight
- 137.8 kDa
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NCBI Accession
- NP_000416
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Pathways
- Synaptic Membrane
Target
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