CD177 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713472

Recombinant CD177 protein expressed in HEK-293 Cells.

Quick Overview for CD177 Protein (Myc-DYKDDDDK Tag) (ABIN2713472)

Target: CD177 (CD177 Molecule (CD177))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This CD177 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD177 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CD177 (CD177 Molecule (CD177))

Alternative Name: CD177

Background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener&aposs granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Molecular Weight: 46.2 kDa

NCBI Accession: NP_065139