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CD1a Protein (CD1a) (Myc-DYKDDDDK Tag)

This Recombinant CD1a protein is expressed in HEK-293 Cells.
Catalog No. ABIN2713480

Quick Overview for CD1a Protein (CD1a) (Myc-DYKDDDDK Tag) (ABIN2713480)

Target

See all CD1a Proteins
CD1a

Protein Type

Recombinant

Origin

  • 6
  • 1
Human

Source

  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This CD1a protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD1a protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CD1a

    Alternative Name

    CD1a

    Background

    This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    35.2 kDa

    NCBI Accession

    NP_001754

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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