CD2AP Protein (Myc-DYKDDDDK Tag)
Quick Overview for CD2AP Protein (Myc-DYKDDDDK Tag) (ABIN2713486)
Target
See all CD2AP (Cd2ap) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD2AP protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD2-associated protein protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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CD2-Associated Protein (Cd2ap) (AA 1-637) protein (His tag)
custom-made Cd2ap Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD2-Associated Protein (Cd2ap) (AA 1-639) protein (His tag)custom-made Cd2ap Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
CD2-Associated Protein (Cd2ap) proteinCd2ap Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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Alternative Name
- CD2-Associated Protein
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Background
- This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
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Molecular Weight
- 71.3 kDa
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NCBI Accession
- NP_036252
Target
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