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CD247 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

This Recombinant CD247 protein is expressed in HEK-293 Cells.
Catalog No. ABIN2713537
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for CD247 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713537)

Target

See all CD247 Proteins
CD247 (CD247 Molecule (CD247))

Protein Type

Recombinant

Origin

  • 13
  • 1
Human

Source

  • 8
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 2

    Purification tag / Conjugate

    This CD247 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD247 / CD3Z (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CD247 (CD247 Molecule (CD247))

    Alternative Name

    Cd247,cd3z

    Background

    The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Molecular Weight

    16.2 kDa

    NCBI Accession

    NP_000725

    Pathways

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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