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F11R Protein

This Recombinant F11R protein is expressed in HEK-293 Cells.
Catalog No. ABIN2713651

Quick Overview for F11R Protein (ABIN2713651)

Target

See all F11R Proteins
F11R (F11 Receptor (F11R))

Protein Type

Recombinant

Origin

  • 14
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  • 1
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Human

Source

  • 11
  • 8
  • 3
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  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Characteristics

    • Recombinant human CD321 / JAM1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone

    Endotoxin Level

    < 0.1 EU per μg protein as determined by LAL test
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Restrictions

    For Research Use only
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 100 mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    F11R (F11 Receptor (F11R))

    Alternative Name

    Cd321,jam1

    Background

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

    Molecular Weight

    23.9 kDa

    NCBI Accession

    NP_058642

    Pathways

    Cell-Cell Junction Organization
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