F11R Protein
Quick Overview for F11R Protein (ABIN2713651)
Target
See all F11R ProteinsProtein Type
Origin
Source
Application
Purity
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Characteristics
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- Recombinant human CD321 / JAM1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 100 mM Glycine, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- F11R (F11 Receptor (F11R))
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Alternative Name
- Cd321,jam1
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Background
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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Molecular Weight
- 23.9 kDa
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NCBI Accession
- NP_058642
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Pathways
- Cell-Cell Junction Organization
Target
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