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CD4 Protein (CD4) (Myc-DYKDDDDK Tag)

This Recombinant CD4 protein is produced in HEK-293 Cells.
Catalog No. ABIN2713704

Quick Overview for CD4 Protein (CD4) (Myc-DYKDDDDK Tag) (ABIN2713704)

Target

See all CD4 Proteins
CD4

Protein Type

Recombinant

Origin

  • 34
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  • 6
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  • 1
  • 1
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  • 1
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Human

Source

  • 27
  • 9
  • 8
  • 3
  • 2
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  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This CD4 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    CD4

    Alternative Name

    CD4

    Background

    This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

    Molecular Weight

    48.3 kDa

    NCBI Accession

    NP_000607

    Pathways

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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