CD46 Protein (CD46) (Transcript Variant D) (His tag)
Quick Overview for CD46 Protein (CD46) (Transcript Variant D) (His tag) (ABIN2713723)
Target
See all CD46 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant D
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Purification tag / Conjugate
- This CD46 protein is labelled with His tag.
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Characteristics
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- Recombinant human CD46 / MCP (transcript variant d) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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CD46 (CD46) (AA 35-329) (Active) protein (His tag)
CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD46 (CD46) (AA 35-343) (Active) protein (His tag)CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD46 (CD46) (AA 35-328) protein (His tag)CD46 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD46 (CD46) (AA 45-344) (Active) protein (His tag)CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD46 (CD46) (AA 1-384) protein (GST tag)CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD46 (CD46) (AA 35-328) (Active) protein (His tag)CD46 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
CD46 (CD46) (AA 35-313) protein (His-IF2DI Tag)CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
CD46 (CD46) (AA 35-313) protein (His tag)CD46 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CD46
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Alternative Name
- Cd46,mcp
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Background
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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Molecular Weight
- 33.83kD
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NCBI Accession
- NP_722548
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Pathways
- Regulation of Actin Filament Polymerization
Target
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