ITGA6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713733

Recombinant ITGA6 protein expressed in HEK-293 Cells.

Quick Overview for ITGA6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713733)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This ITGA6 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human CD49f / ITGA6 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: Cd49f,itga6

Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Molecular Weight: 117.2 kDa

NCBI Accession: NP_000201

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex