CD59 Protein (CD59) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for CD59 Protein (CD59) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713744)
Target
See all CD59 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Protein Characteristics
- Transcript Variant 2
-
Purification tag / Conjugate
- This CD59 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human CD59 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
CD59 (CD59) (AA 26-102) (Active) protein (His tag)
CD59 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
CD59 (CD59) (AA 1-128) protein (GST tag)CD59 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CD59 (CD59) protein (His tag)CD59 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
CD59 (CD59) (AA 26-102) protein (Fc Tag)CD59 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- CD59
-
Alternative Name
- CD59
-
Background
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
-
Molecular Weight
- 11.6 kDa
-
NCBI Accession
- NP_000602
-
Pathways
- Complement System
Target
-
