CHMP2A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for CHMP2A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2713981)
Target
See all CHMP2A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This CHMP2A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CHMP2A / BC2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
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Alternative Name
- Chmp2a,bc2
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Background
- CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
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Molecular Weight
- 24.9 kDa
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NCBI Accession
- NP_940818
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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