ACTC1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714587

This Recombinant ACTC1 protein is expressed in HEK-293 Cells.

Quick Overview for ACTC1 Protein (Myc-DYKDDDDK Tag) (ABIN2714587)

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This ACTC1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human alpha 1 cardiac muscle Actin / ACTC1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Alternative Name: alpha 1 Cardiac Muscle Actin,actc1

Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Molecular Weight: 41.8 kDa

NCBI Accession: NP_005150

Pathways: Myometrial Relaxation and Contraction