AMN Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714665

This Recombinant AMN protein is expressed in HEK-293 Cells.

Quick Overview for AMN Protein (Myc-DYKDDDDK Tag) (ABIN2714665)

Target: AMN (Amnionless (AMN))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This AMN protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human amnionless / AMN protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: AMN (Amnionless (AMN))

Alternative Name: Amnionless,amn

Background: The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.

Molecular Weight: 45.6 kDa

NCBI Accession: NP_112205

Pathways: Lipid Metabolism