ATP2B2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ATP2B2 Proteins
- ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ATP2B2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ATP2B2 / PMCA2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ATP2B2 Protein
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ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2) (AA 1-1198) protein (His tag)
custom-made ATP2B2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2) (AA 1-1243) protein (His tag)custom-made ATP2B2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
- Alternative Name
- Atp2b2,pmca2 (ATP2B2 Products)
- Background
- The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Molecular Weight
- 136.7 kDa
- NCBI Accession
- NP_001001331
- Pathways
- Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process
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