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ATP7B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant ATP7B protein is produced in HEK-293 Cells.
Catalog No. ABIN2715066
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
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Quick Overview for ATP7B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2715066)

Target

See all ATP7B Proteins
ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Protein Type

Recombinant

Origin

  • 4
  • 3
Human

Source

  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This ATP7B protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human ATP7B (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

    Alternative Name

    Atp7b

    Background

    This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

    Molecular Weight

    157.1 kDa

    NCBI Accession

    NP_000044

    Pathways

    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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