ATP7B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for ATP7B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2715066)
Target
See all ATP7B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This ATP7B protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ATP7B (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
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Alternative Name
- Atp7b
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Background
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
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Molecular Weight
- 157.1 kDa
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NCBI Accession
- NP_000044
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Pathways
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
Target
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