BACE1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715129

This Recombinant BACE1 protein is produced in HEK-293 Cells.

Quick Overview for BACE1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2715129)

Target: BACE1 (Beta-secretase 1 (BACE1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant A

Purification tag / Conjugate: This BACE1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human BACE1 (transcript variant a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: Bace1

Background: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.

Molecular Weight: 51 kDa

NCBI Accession: NP_036236