BAIAP2L1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715144

This Recombinant BAIAP2L1 protein is produced in HEK-293 Cells.

Quick Overview for BAIAP2L1 Protein (Myc-DYKDDDDK Tag) (ABIN2715144)

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This BAIAP2L1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human BAIAP2L1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Alternative Name: Baiap2l1

Background: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Molecular Weight: 56.7 kDa

NCBI Accession: NP_061330

Pathways: Regulation of Actin Filament Polymerization