Catalog No. ABIN2715167
$1,112.40
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20 μg
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Quick Overview for BBS4 Protein (Myc-DYKDDDDK Tag) (ABIN2715167)
Target
See all BBS4 Proteins
BBS4
(Bardet-Biedl Syndrome 4 (BBS4))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This BBS4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human BBS4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) protein (GST tag)
BBS4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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Alternative Name
- Bbs4
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Background
- This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein&aposs shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 58.1 kDa
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NCBI Accession
- NP_149017
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Pathways
- Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
Target
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