BCOR Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715205

This Recombinant BCOR protein is expressed in HEK-293 Cells.

Quick Overview for BCOR Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2715205)

Target: BCOR (BCL6 Co-Repressor (BCOR))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 3

Purification tag / Conjugate: This BCOR protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Bcl-6 corepressor (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BCOR (BCL6 Co-Repressor (BCOR))

Alternative Name: Bcl-6 Corepressor

Background: The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010].

Molecular Weight: 188 kDa

NCBI Accession: NP_001116855