EXO5 Protein (Myc-DYKDDDDK Tag)
Quick Overview for EXO5 Protein (Myc-DYKDDDDK Tag) (ABIN2719347)
Target
See all EXO5 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This EXO5 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Exonuclease V protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- EXO5 (Exonuclease 5 (EXO5))
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Alternative Name
- Defects in Morphology 1 Homolog (S. Cerevisiae) (Dem1)
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Background
- The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5&apos-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage.
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Molecular Weight
- 41.6 kDa
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NCBI Accession
- NP_073611
Target
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