Der1-Like Domain Family, Member 2 (DERL2) protein (Myc-DYKDDDDK Tag)
Quick Overview for Der1-Like Domain Family, Member 2 (DERL2) protein (Myc-DYKDDDDK Tag) (ABIN2719402)
Target
See all Der1-Like Domain Family, Member 2 (DERL2) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- Myc-DYKDDDDK Tag
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Characteristics
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- Recombinant human Derlin-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Der1-Like Domain Family, Member 2 (DERL2)
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Alternative Name
- Derlin-2
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Background
- Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008].
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Molecular Weight
- 27.4 kDa
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NCBI Accession
- NP_057125
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Pathways
- ER-Nucleus Signaling, Feeding Behaviour
Target
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