DTX2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Quick Overview for DTX2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2719807)
Target
See all DTX2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Purification tag / Conjugate
- This DTX2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human DTX2 / RNF58 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Deltex Homolog 2 (DTX2) (AA 1-619) protein (His tag)
custom-made DTX2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Deltex Homolog 2 (DTX2) (AA 1-622) protein (His tag)custom-made DTX2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Deltex Homolog 2 (DTX2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DTX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Deltex Homolog 2 (DTX2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DTX2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- DTX2 (Deltex Homolog 2 (DTX2))
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Alternative Name
- Dtx2,rnf58
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Background
- Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProtKB/Swiss-Prot Function]
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Molecular Weight
- 67.1 kDa
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NCBI Accession
- NP_001096065
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Pathways
- Notch Signaling
Target
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