EDAR Protein (Myc-DYKDDDDK Tag)
Quick Overview for EDAR Protein (Myc-DYKDDDDK Tag) (ABIN2719928)
Target
See all EDAR ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This EDAR protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human EDAR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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Alternative Name
- Edar
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Background
- This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
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Molecular Weight
- 45.8 kDa
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NCBI Accession
- NP_071731
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Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
Target
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