ELAC2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2720116

This Recombinant ELAC2 protein is expressed in HEK-293 Cells.

Quick Overview for ELAC2 Protein (Myc-DYKDDDDK Tag) (ABIN2720116)

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This ELAC2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human ELAC2 / HPC2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Alternative Name: Elac2,hpc2

Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3&apos trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 92 kDa

NCBI Accession: NP_060597