MVB12B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
This Recombinant MVB12B protein is expressed in HEK-293 Cells.
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Catalog No. ABIN2720746
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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United States
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Quick Overview for MVB12B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2720746)
Target
See all MVB12B Proteins
MVB12B
(Multivesicular Body Subunit 12B (MVB12B))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This MVB12B protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human FAM125B (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Multivesicular Body Subunit 12B (MVB12B) (AA 1-221) protein (GST tag)
MVB12B Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
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Alternative Name
- Fam125b
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Background
- The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 24.3 kDa
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NCBI Accession
- NP_001011703
Target
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