Fascin Protein (FSCN1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2720880

This Recombinant Fascin protein is produced in HEK-293 Cells.

Quick Overview for Fascin Protein (FSCN1) (Myc-DYKDDDDK Tag) (ABIN2720880)

Target: Fascin (FSCN1)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Fascin protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Fascin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin&aposs lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Molecular Weight: 54.3 kDa

NCBI Accession: NP_003079