GAMT Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721681

This Recombinant GAMT protein is produced in HEK-293 Cells.

Quick Overview for GAMT Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721681)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This GAMT protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human GAMT (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: Gamt

Background: The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Molecular Weight: 26.1 kDa

NCBI Accession: NP_000147