Gephyrin Protein (GPHN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for Gephyrin Protein (GPHN) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721820)
Target
See all Gephyrin (GPHN) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This Gephyrin protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Gephyrin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Gephyrin (GPHN)
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Alternative Name
- Gephyrin
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Background
- This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described however, the full-length nature of all transcript variants is not currently known.
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Molecular Weight
- 83.3 kDa
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NCBI Accession
- NP_065857
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Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
Target
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