GLE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
This Recombinant GLE1 protein is expressed in HEK-293 Cells.
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Catalog No. ABIN2721895
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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United States
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Quick Overview for GLE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721895)
Target
See all GLE1 Proteins
GLE1
(GLE1 RNA Export Mediator (GLE1))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This GLE1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human GLE1 / GLE1L (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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GLE1 RNA Export Mediator (GLE1) (AA 1-698) protein (GST tag)
GLE1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- GLE1 (GLE1 RNA Export Mediator (GLE1))
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Alternative Name
- Gle1,gle1l
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Background
- This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 79.7 kDa
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NCBI Accession
- NP_001003722
Target
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