Glutaredoxin 2 Protein (GRX2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722017

This Recombinant Glutaredoxin 2 protein is produced in HEK-293 Cells.

Quick Overview for Glutaredoxin 2 Protein (GRX2) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722017)

Target: Glutaredoxin 2 (GRX2)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Glutaredoxin 2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Glutaredoxin-2 / GLRX2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Glutaredoxin 2 (GRX2)

Alternative Name: Glutaredoxin-2,glrx2

Background: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Molecular Weight: 18.5 kDa

NCBI Accession: NP_057150

Pathways: Cell RedoxHomeostasis