GRB14 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722227

This Recombinant GRB14 protein is produced in HEK-293 Cells.

Quick Overview for GRB14 Protein (Myc-DYKDDDDK Tag) (ABIN2722227)

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This GRB14 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human GRB14 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Alternative Name: Grb14

Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

Molecular Weight: 60.8 kDa

NCBI Accession: NP_004481