H2AFB1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722379

Recombinant H2AFB1 protein expressed in HEK-293 Cells.

Quick Overview for H2AFB1 Protein (Myc-DYKDDDDK Tag) (ABIN2722379)

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This H2AFB1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human H2AFB1 / H2A.Bbd protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene.

Molecular Weight: 12.5 kDa

NCBI Accession: NP_001017990

Pathways: Telomere Maintenance