Quick Overview for HDAC3 Protein (Myc-DYKDDDDK Tag) (ABIN2722499)
Target
See all HDAC3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This HDAC3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human HDAC3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Histone Deacetylase 3 (HDAC3) (AA 1-428) protein (GST tag)
HDAC3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 3 (HDAC3) (AA 319-428) protein (GST tag)HDAC3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 3 (HDAC3) (AA 1-428), (full length) protein (His-SUMO Tag)HDAC3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Alternative Name
- Hdac3
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Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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Molecular Weight
- 48.7 kDa
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NCBI Accession
- NP_003874
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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