HDAC6 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722518

This Recombinant HDAC6 protein is produced in HEK-293 Cells.

Quick Overview for HDAC6 Protein (Myc-DYKDDDDK Tag) (ABIN2722518)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This HDAC6 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human HDAC6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: Hdac6

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Molecular Weight: 131.2 kDa

NCBI Accession: NP_006035

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling