IL1RAP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for IL1RAP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2723387)
Target
See all IL1RAP ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This IL1RAP protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IL1RAP (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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Alternative Name
- Il1rap
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Background
- Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
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Molecular Weight
- 40.8 kDa
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NCBI Accession
- NP_608273
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Pathways
- NF-kappaB Signaling, Growth Factor Binding
Target
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