ING3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for ING3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2723448)
Target
See all ING3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This ING3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ING3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) protein (GST tag)
ING3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inhibitor of Growth Family, Member 3 (ING3) (AA 1-418) protein (GST tag)ING3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inhibitor of Growth Family, Member 3 (ING3) (AA 1-92) protein (His-IF2DI Tag)ING3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
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Alternative Name
- Ing3
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Background
- The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
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Molecular Weight
- 46.6 kDa
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NCBI Accession
- NP_061944
Target
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