INSIG2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723492

Recombinant INSIG2 protein expressed in HEK-293 Cells.

Quick Overview for INSIG2 Protein (Myc-DYKDDDDK Tag) (ABIN2723492)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This INSIG2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human INSIG2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: Insig2

Background: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Molecular Weight: 24.6 kDa

NCBI Accession: NP_057217

Pathways: ER-Nucleus Signaling