IL16 Protein (Transcript Variant 1)
Quick Overview for IL16 Protein (Transcript Variant 1) (ABIN2723626)
Target
See all IL16 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
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Characteristics
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- Recombinant human Interleukin-16 / IL16 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Biological Activity Comment
- Determined by its ability ot chemoattract human CD4+ T-Lymphocytes using a concentration range of 50.0-100.0 ng/ml.
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Interleukin 16 (IL16) (AA 1-1322) protein (His tag)
custom-made IL16 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1-1332) protein (His tag)custom-made IL16 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)IL16 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 16 (IL16) (Active) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 16 (IL16) (AA 502-631) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
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Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL16 (Interleukin 16 (IL16))
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Alternative Name
- Interleukin-16,il16
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Background
- Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells. [UniProtKB/Swiss-Prot Function]
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Molecular Weight
- 12.4 kDa
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NCBI Accession
- NP_004504
Target
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