IRAK4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for IRAK4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2723784)
Target
See all IRAK4 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This IRAK4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IRAK4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-460) protein (His tag)
custom-made IRAK4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-459) protein (His tag)custom-made IRAK4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-460) protein (GST tag)IRAK4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA, KAA
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-196) protein (GST tag)IRAK4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-130) protein (GST tag)IRAK4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (Active) protein (His tag)IRAK4 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Alternative Name
- Irak4
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Background
- This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 51.3 kDa
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NCBI Accession
- NP_057207
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Pathways
- NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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