Quick Overview for IRF4 Protein (Myc-DYKDDDDK Tag) (ABIN2723795)
Target
See all IRF4 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IRF4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IRF4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Interferon Regulatory Factor 4 (IRF4) (AA 1-451) protein (His tag)
custom-made IRF4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interferon Regulatory Factor 4 (IRF4) (AA 1-450) protein (His tag)custom-made IRF4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interferon Regulatory Factor 4 (IRF4) (AA 1-451) protein (GST tag)IRF4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 4 (IRF4) proteinIRF4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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Alternative Name
- Irf4
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Background
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(614)(p25q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
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Molecular Weight
- 51.6 kDa
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NCBI Accession
- NP_002451
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Pathways
- Chromatin Binding
Target
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