KDM4C Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723934

This Recombinant KDM4C protein is produced in HEK-293 Cells.

Quick Overview for KDM4C Protein (Myc-DYKDDDDK Tag) (ABIN2723934)

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This KDM4C protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human JMJD2C / KDM4C protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: Jmjd2c,kdm4c

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants.

Molecular Weight: 119.8 kDa

NCBI Accession: NP_055876

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect