JMJD6 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723938

This Recombinant JMJD6 protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for JMJD6 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2723938)

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This JMJD6 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human JMJD6 / PTDSR (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Lawrence, Conderino, Rieder: "Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of Jumonji C-domain containing protein 6 in RHA demethylation." in: Virology, Vol. 452-453, pp. 1-11, (2014) (PubMed).

Target Details

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: Jmjd6,ptdsr

Background: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47.4 kDa

NCBI Accession: NP_001074930