KIAA0562 Protein (KIAA0562) (Myc-DYKDDDDK Tag)
Quick Overview for KIAA0562 Protein (KIAA0562) (Myc-DYKDDDDK Tag) (ABIN2724200)
Target
Protein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This KIAA0562 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human KIAA0562 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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KIAA0562 (KIAA0562) (AA 1-554) protein (GST tag)
KIAA0562 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
KIAA0562 (KIAA0562) (AA 29-181) protein (His-IF2DI Tag)KIAA0562 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KIAA0562
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Alternative Name
- Kiaa0562
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Background
- This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia.
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Molecular Weight
- 104.3 kDa
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NCBI Accession
- NP_055519
Target
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