Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

KLHL3 Protein (Myc-DYKDDDDK Tag)

This Recombinant KLHL3 protein is produced in HEK-293 Cells.
Catalog No. ABIN2724309

Quick Overview for KLHL3 Protein (Myc-DYKDDDDK Tag) (ABIN2724309)

Target

See all KLHL3 Proteins
KLHL3 (Kelch-Like 3 (KLHL3))

Protein Type

Recombinant

Origin

  • 3
  • 2
Human

Source

  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This KLHL3 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human KLHL3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
  • Want other Options for this Protein ?

    !
    Discover Our Predefined Custom Proteins and Custom Protein Services!
    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    Price starts at $20,480.57

    Your project requires further customization? Contact us and discover our custom protein solutions

  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    KLHL3 (Kelch-Like 3 (KLHL3))

    Alternative Name

    Klhl3

    Background

    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D) a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Molecular Weight

    64.8 kDa

    NCBI Accession

    NP_059111
You are here:
Chat with us!