KPNA6 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724408

This Recombinant KPNA6 protein is produced in HEK-293 Cells.

Quick Overview for KPNA6 Protein (Myc-DYKDDDDK Tag) (ABIN2724408)

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This KPNA6 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human KPNA6 / Importin alpha-7 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Alternative Name: Kpna6,importin alpha-7

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.

Molecular Weight: 59.8 kDa

NCBI Accession: NP_036448

Pathways: Protein targeting to Nucleus