LACE1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724451

This Recombinant LACE1 protein is expressed in HEK-293 Cells.

Quick Overview for LACE1 Protein (Myc-DYKDDDDK Tag) (ABIN2724451)

Target: LACE1 (Lactation Elevated 1 (LACE1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This LACE1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human LACE1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LACE1 (Lactation Elevated 1 (LACE1))

Alternative Name: Lace1

Background: This gene encodes a mitochondrial integral membrane protein that plays a role in mitochondrial protein homeostasis. The protein contains a P-loop motif and a five-domain structure that is conserved in fly, yeast, and bacteria. It functions to mediate the degradation of nuclear-encoded complex IV subunits. Two conserved estrogen receptor binding sites are located within 2.5 kb of this gene. Polymorphisms in this gene have been associated with bipolar disorder. Alternative splicing results in multiple transcript variants.

Molecular Weight: 54.7 kDa

NCBI Accession: NP_660358